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Re2 Coffea Arabica Peptide - circular multi-benefits scalp care ingredient for hydration, soothing and more

Re2 Coffea Arabica Peptide

AI-designed and bio-sourced active ingredient for scalp care

Circular by Nature. Intelligent by Design.

Every ingredient has a story. Re2 Coffea Arabica Peptide begins where most stories end — with what’s left behind. Upcycled coffee grounds become the starting point for a new kind of scalp care active, designed to meet today’s top consumer needs for hydration and soothing, and to go further, supporting overall scalp comfort through multifunctional performance.

 Key features and benefits 

Re2 Coffea Arabica Peptide is a coffee-derived peptide active designed to bring multiple scalp-care benefits together in one ingredient. Features and benefits include: 

  • Upcycled, traceable origin: derived from coffee grounds sourced from a plantation in Pu’er, China.
  • Made for skin-inspired scalp routines: A single multi-purpose scalp-care active aligned consumer expectations for clean beauty.
  • Proven hydration & softness: increases scalp hydration up to 51.2% and scalp softness up to 57.1%.
  • Comfort & scalp barrier support: helps improve softness and supports barrier comfort, including Transepidermal water loss (TEWL) decrease.
  • Calming benefits: supports redness reduction and anti-inflammatory activity for a calmer-looking, more comfortable scalp.
  • Supports hair loss reduction.

The story behind Re2 Coffea Arabica Peptide

Re2 Coffea Arabica Peptide - Circular by Nature Intelligent by Design - Circular Multi-Benefit Scalp Care Ingredient

 

From coffee grounds to a purposeful scalp-care active

In today’s beauty market, naturality alone is not enough, and purpose cannot come at the cost of performance. Re2 Coffea Arabica Peptide brings these priorities together: sourced from a coffee plantation in Pu’er, China, it is made by upcycling coffee grounds into a high-performing peptide ingredient. This origin supports brands looking to combine purpose and performance in their formulations.

AI-guided screening to identify the best coffee peptides for scalp care 

The ingredient’s performance is built into its peptide design. Artificial intelligence was used to screen natural coffee proteins and reveal the most promising peptide sequences - those most beneficial for scalp health - hidden within nature’s complexity.

After reproducing these peptides via enzymatic digestion (a natural process that uses enzymes to break proteins into smaller peptide fragments), they were combined into a single ingredient designed to deliver multiple scalp benefits: improved hydration and softness, enhanced barrier function, reduced transepidermal water loss (TEWL) and redness, and anti-inflammatory activity.

Re2 Coffea Arabica Peptide - Multi-Benefit Scalp Care Ingredient supported by shampoo tests

Applying skin care science to the scalp

 

The skinification of hair is a trend that reflects the growing expectation that scalp care should follow the same principles as facial skincare, supporting hydration, barrier function and comfort. As consumers adopt scalp serums and leave-on treatments, they increasingly look for skincare-relevant benefits such as reduced transepidermal water loss (TEWL), improved barrier integrity and less visible redness. Re2 Coffea Arabica Peptide aligns with this shift by targeting multiple scalp fundamentals in one single active.

FAQs

What benefits do coffee grounds bring to scalp care ingredients?

In hair care and scalp care, coffee grounds can be transformed into actives that support hydration, soothing, softness, and scalp comfort when carefully refined and validated. In Re2 Coffea Arabica Peptide, coffee ground becomes the foundation of a targeted peptide blend designed for scalp-first routines, with traceability reinforcing transparency.

Is Re2 Coffea Arabica Peptide derived from coffee grounds?

Yes. Re2 Coffea Arabica Peptide is up-cycled from coffee grounds, sourced from a sustainable coffee plantation in Pu’er, China, whose beans are fully traceable.

What makes Re2 Coffea Arabica Peptide different from other scalp care actives?

Re2 Coffea Arabica Peptide integrates an upcycled biomass origin with AI-guided, biomarker-targeted peptides designed to support multiple scalp benefits in one ingredient. It combines circular sourcing, Artificial Intelligence, and performance validation within a single ingredient.

How was AI used to create Re2 Coffea Arabica Peptide?

Re2 Coffea Peptide is the result of AI-powered peptide prediction and molecular docking. It shows how AI can help researchers screen natural materials for promising sequences and prioritize candidates for laboratory validation. This approach helped target biomarkers associated with key scalp benefits to translate coffee ground extract into an optimal peptide blend.

How to reduce hair  breakage in shampoo?

In a 28-day clinical study, a shampoo containing 2% Re2 Coffea Arabica Peptide reduced hair loss count by 29% (vs 16% placebo).

What is transepidermal water loss (TEWL)?

Transepidermal water loss (TEWL) measures water evaporation through the skin; lower TEWL is commonly associated with improved barrier function.

How to formulate with Re2 Coffea Arabica Peptide?

Use Re2 Coffea Arabica Peptide at 0.5–2.0% in shampoos, conditioners, styling products, or hair/scalp treatments, adding it under 30°C with gentle mixing and maintaining pH at 4.0–7.5. It is a water-soluble liquid with a 24-month shelf life when stored at 10–30°C protected from light, humidity, and heat.